Feto-Maternal Incompatibility in the ABO System at EHS Nouar Fadela

ABO Bloods group incompatibility in recurrent abortion

Abstract Background A vast variety of factors may cause recurrent pregnancy loss. Blood group incompatibility of parents could cause abortion. The examination of couples or twins, blood groups showed that the blood group incompatibility can affect adversely the outcome of pregnancy. Couples with blood group incompatibility are more involved in spontaneous miscarriage. Antigenes in two differe...

Dynamics of immunoglobulins at the feto-maternal interface.

Transplacental transport of maternal immunoglobulin G (IgG) to the developing fetus is extremely important in the protection of the newborn from infection. Although the exact mechanisms of the selective and active transfer of IgG across the placental barrier are not fully understood, receptors for the Fc part of IgG (FcgammaRs) in the placenta are believed to play a key role. Several known Fc r...

ABO incompatibility: which one matters?

Molecular Cross-Talk at the Feto-Maternal Interface.

Molecular cross-talk at the feto-maternal interface occurs between many different cell types, including uterine leukocytes, extravillous trophoblast cells, and uterine spiral arteries, is essential for the establishment and maintenance of pregnancy. This review concentrates on human pregnancy and examines three main areas in which cross-talk occurs; immune tolerance, regulation of extravillous ...

Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface

The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover recent aspects of immune privilege and the innate immune system at the feto-maternal interface, citing examples of the role played by mi...